منابع مشابه
Conformational dynamics of substrate in the active site of cytochrome P450 BM-3/NPG complex: insights from NMR order parameters.
Cytochrome P450 enzymes catalyze selective oxidation of a wide variety of hydrophobic substrates.1 The low-temperature crystal structure P450 BM-32 bound to N-palmitoylglycine (NPG) shows the substrate bound distant to the iron in a position that is evidently unproductive for chemistry. UV-vis absorbance measurements indicating a spin-state transition and associated studies3 of cytochrome P450 ...
متن کاملNew Triterpenoids from Peucedanum ruthenicum
From hexanic extract of aerial parts of Peucedanum ruthenicum M. Bieb (Apiaceae) collected from Mazandaran province of Iran, four triterpenoids namely taraxasterol, y-taraxasterol, poriferasterol and b-sitosterol have been isolated by column chromatography, thin layer chromatography, and crystallization. Their structures were elucidated by spectroscopic methods (UV, IR, MS, 1H and 13C-N...
متن کاملMonolithic NPG nanoparticles with large surface area, tunable plasmonics, and high-density internal hot-spots.
Plasmonic metal nanostructures have shown great potential in sensing, photovoltaics, imaging and biomedicine, principally due to the enhancement of local electric field by light-excited surface plasmons, i.e., collective oscillation of conduction band electrons. Thin films of nanoporous gold have received a great deal of interest due to the unique 3-dimensional bicontinuous nanostructures with ...
متن کاملEnhanced single molecule fluorescence and reduced observation volumes on nanoporous gold (NPG) films.
We report single molecule fluorescence studies on nanoporous gold films. We observed dramatically enhanced intensities in individual immobilized fluorophores and reduced effective observation volumes in the nanopores. The enhanced localized plasmon field existing in the "nanovoid" regions can be visualized from the overlaid mapping image derived from surface reflectance and fluorescence emission.
متن کاملNEW RECORDS OF ENTOMOPHTHORALEAN FUNGI FROM IRAN
Among 170 insects infected by fungal pathogens, obtained during 2003-08 from three Northern provinces of Iran (Mazandaran, Gilan and Golestan), eight taxa of entomophthoralean fungi were identified including four pathogens of dipteran insects: Entomophaga tipulae was found on a crane fly, Entomophthora muscae was seen on five flies attached to broadbean leaves, Pandora bulata was observed only ...
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ژورنال
عنوان ژورنال: Nature Medicine
سال: 2013
ISSN: 1078-8956,1546-170X
DOI: 10.1038/nm.3069